Proteins that are functionally less important for the survival of an organism generally evolve faster than more important proteins.
Proteins serve as the building blocks for all of life's essential processes. The proteins evolve along with the genes that create them, adding new functionality or features that may potentially result in the development of new species.
The mutation of amino acid-coding nucleotides and the stabilization of novel variations in the population are the two phases required for protein evolution.
The stability of a protein's folded structure, how well it prevents aggregation, and how well it is chaperoned all affect how quickly it evolves. According to the studies, the degree of a protein's expression has a greater influence on its evolutionary rate than does the protein's functional significance.
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Answer:
The heart and lungs contain cells that contain the same information but they do different specialized functions
Explanation:
Answer:
All the given statements are correct except b.
Antimicrobial resistance (AMR) refers to the ability of a microorganism to grow in the presence of drug or a chemical that would normally limit its growth or kill it.
It makes it difficult for the existing drugs to eliminate the infection as they become less effective against the microbe.
There are five major mechanisms by which a microbe attains resistance against antimicrobial chemical or drug:
- Drug modification or inactivation: A microbial enzyme inactivates the antimicrobial agent. For example, few bacteria produce β-lactamases which provide multi-resistance against β-lactam antibiotics such as penicillin, cephalosporin etc.
- Alteration or modification of target site: An altered target site prevents the antimicrobial agent from binding to its target. For example, alteration of penicillin binding protein (PBP) in Methicillin-resistant <em>Staphylococcus aureus </em>(MRSA).
- Alteration of metabolic pathway: The microbe uses an alternative pathway to circumvent the blocked pathway. For example, sulfonamides-resistant bacteria started using preformed folic acid in place of para-aminobenzoic acid (PABA).
- Decreased drug accumulation: Microbial efflux pumps remove the antimicrobial agent (before it could do any damage) by pumping it out of the cell.
- Decrease in cell permeability: The permeability of the microbial envelope to the antimicrobial agent is decreased
