Well, if you get exhausted very easily while running and you are in shape, I would say that might be asthma. Also if while you are running, your lungs start to feel like they are being pushed down.
No, a long as a dairy cow has been pregnant once, the cow will continue producing milk as long as it is continually milked whether it is currently pregnant or not
Tell the friend to be careful not to take too much. It does not sound like they have a negative relationship with this drug, nor serious health issues. Telling them to be cautious is the most helpful/appropriate thing to say here.