Answer:
The primary purpose of the Supremacy Clause is It establishes that the federal constitution, and federal law generally, take precedence over state laws, and even state constitutions.
The appropriate response is world-system theory. It is a hypothesis of modernization by Immanuel Wallerstein in which the spread of free enterprise is viewed as delivering a universal division of work between more-created and less-created countries. As indicated by this view, the more-created countries control the components or generation and less-created countries fill in as wellsprings of modest work and crude materials.
Geographic isolation could be caused by a number of environmental factors. If a population of people or species live on an island, amongst mountains, in difficult to navigate terrain, or deep into rainforest or forests generally these groups could experience geographic isolation. Geographic largely occurs if a population or group of people or animals live in a remote region of the world that has little access to others due to any number of geographic features.