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larisa [96]
3 years ago
13

Why is it significant that the four missense mutations are found in the extracellular and intracellular domains of th eprotein

Biology
1 answer:
Mariana [72]3 years ago
4 0
What is it significant that the eprotein
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A signaling pathway that stimulates cellular growth and division is positively regulated by a GTPase encoded by an autosomally l
Romashka-Z-Leto [24]

Answer:

The correct answer is: a.

Explanation:

  • A Diploid organism possess two copies ( also called alleles) of each  autosomal gene, of which one copy of the gene is obtained from one of its parents and the other copy from its other parent.
  • During the process of replication, one of the alleles of the GTPase encoding gene undergoes a mis-sense mutation.
  • A Mis-sense mutation can be defined as a non-synonymous mutation in which one of the nucleotide in the sequence of the gene gets altered such that it causes a change in the amino acid encoded by the codon (triplet nucleotide message encoding for a single amino acid)  formed by the mutated nucleotide. A single amino acid change in the protein, if occurs in the functional site of the protein, can render a protein non-functional.
  • Hence, the mis-sense mutation in one of the alleles encoding for the GTPase gene causes the resulting protein produced from the mutated allele to have drastically reduced function (1%).
  • A heterozygous cell is one which has one copy of the normal allele and the other copy of the mutated allele of the GTPase encoding gene.
  • As one copy of the normal GTPase allele is present in such an individual, it can produce the normal GTPase protein that can assist in the process of cell growth and division.
  • Hence, the phenotype(expressed character) of  the heterozygous cell will not be affected due to the mutation and it will be able to grow and divide normally.
8 0
2 years ago
A female may neglect, kill or eat their offspring because of ______<br> HELPPP PLEASEEE
Georgia [21]

Answer:

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Explanation:

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2 years ago
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The scientific method provides the framework for all scientific research, including nutrition science. Choose the statement belo
Andrews [41]

Answer:

1) d. observe phenomenon; generate hypothesis, conduct experiment, accept, reject, or modify hypothesis.

C. A study that compares a aroup of people with diabetes to a similar aroup of people without diabetes is an example of a case-control study.

Explanation:

Scientific method is a step by step procedure ranging from observing a problem to actual experimentation that aims at investigating a problem. The steps involved in the scientific method are as follows:

a)observe phenomenon; This precedes every experiment in the scientific method.

b) generate hypothesis: This is a testable explanation given as a possible solution to the observed problem.

c) conduct experiment: The hypothesis is tested via experimentation.

d) accept, reject, or modify hypothesis: Based on the result of the experiment, the hypothesis can be rejected, accepted or even modified.

Question 2:

Case control study is a type of study design that uses or compares a group of affected individuals (by a disease) called CASES and unaffected individuals called CONTROL. In this case, A study that compares a group of people with diabetes (cases) to a similar aroup of people without diabetes (control) is an example of a case-control study.

7 0
3 years ago
A pattern of reproduction and growth in a one- celled organism is shown below. Nucleus Which statement best describes this patte
iogann1982 [59]
It is a. all genetic material comes from one parent
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2 years ago
How has the cost of a 30-second Super Bowl commercial grown over time?
ludmilkaskok [199]

Answer: increase

Explanation:

it has increased every Superbowl they have the population of the crowd gets bigger and bigger every year.  yes it has grown at a constant rate of change?

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