OBJECTIVES: To analyze the occurrence and types of neoplasias that have developed in patients submitted to orthotopic heart transplantation in the Cardiac Transplantation Program of the Paulista School of Medicine, Federal University of São Paulo.
METHODS: The present study presents an observational analysis of 106 patients submitted to orthotopic heart transplantation from November 1986 to September 2002, who survived for more than 30 days after the procedure. The immunosuppressive regimen consisted of triple therapy with cyclosporin A, azathioprine and corticosteroid. Only two patients received, in addition to triple therapy, the addition of orthoclone OKT-3. The mean follow-up period was 61.4 months. (variation from two months to 192 months).
RESULTS: Twenty-three patients (21.3%) developed neoplasias, of which 56.5% had skin neoplasms, 30.1% had solid tumors and 13.4% had post-transplantation lymphoproliferative disease (PTLD). The mean interval between transplantation and the diagnosis of neoplasia was: skin - 54.9 months, solid tumors - 24.8 months and DLPT - 70.3 months.
CONCLUSIONS: The occurrence of malignant neoplasms was relatively common in the analyzed population. Skin cancer prevailed in relation to other neoplasms and solid tumors were more diagnosed than lymphoproliferative diseases in this series of patients.
A - Not a knocker but Marley's face
This shows that the knocker transformed to the supernatural by becoming not what it was - but the face of his dead co-worker.
Of course! For the social issue I picked gun violence for you :) Gun violence is a very important issue in society,Guns cause tons of harm. There has been over 582 mass shootings in 2020 alone! There needs to be a safer and difficult way to get ahold of a gun. Due to the lack of security of who gets a gun these shootings are a cause of it causing harm to others.
Answer :
Slave women were expected to work in the fields with the men, not take care of the home life.
They were apportioned almost the same task given to men, not considering their gender. In Africa, woman's primary social role was that of being a mother (tending the kids and making meals in the home). In slavery, this aspect of African womanhood was debased. They were however treated a bit softly whenever they are pregnant, or have just given birth.
