Yes, that is 100% true that the<span> regular heavy drinkers usually have to drink more and more in order to have the same effect.
The reason is that when they drink regularly, their brain gets used to the alcohol and it doesn't have any effect at that certain amount which they intake. So when they feel that taking that much amount of alcohol does feel them good, they drink more and more and there comes a stage when alcohol doesn't have any effect on them.</span>
Energy production depends on metabolic pathway and ATP yield, with fats having the highest ATP yield with ketone bodies,followed by Carbohydrates then proteins.
Energy produced by one glucose molecule yields final ATP of 5-7 through glycolysis and 17-25 through citric cycle.
Proteins energy prooduction is considered to be more healthy because unlike fats and carbohydrates they are not stored but used up immediately by the body.
I hope this is will help
