The external structures of the prokaryotic cell include a plasma membrane, cell wall, and capsule (or slime layer).
        
             
        
        
        
The time period being referred to is the sensitive period. This time period is also referred to as the critical period. The importance of a critical period is such that it must involve certain stimuli from which an organisms learns and acquires traits. If some of these stimuli are not present in the critical period, the organism has difficulty acquiring the trait or skill, and may even find it to be impossible to learn the skill.
        
                    
             
        
        
        
Having two copies of the mutated genes cause sickle cell anemia, but having just one copy does not, and can actually protect against malaria - an example of how mutations are sometimes beneficial. 
The majority of mutations have neither negative nor positive effects on the organism in which they occur. These mutations are called neutral mutations. Examples include silent point mutations. They are neutral because they do not change the amino acids in the proteins they encode.
Hope this helped :)
        
             
        
        
        
The best example of hypothesis which leads to new experiment methods was done by Morgan where he used fruit flies.
Thomas Hunt Morgan continues on genetic research which is of Gregor Mendel.