I'm not sure if you made a typo or not but in the current context I can only see negligible being relevant.
Isolationism was the policy that kept them from joining the League of Nations. Isolationism is when a group stays away from or ignores all people in that group. Mainly political matters of other countries.
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Answer:
1534
Explanation:
In England, the Reformation began with Henry VIII's quest for a male heir.
The election was between John Adams and Thomas Jefferson. It was a battle between Federalists and the Democratic-Republicans. Thomas Jefferson win supporting the Democratic-Republicans. John Adams lost who supported the Federalists. So because of Jefferson we now have the Democratic-Republican party.