The south improvement company in 1872 caused rockefeller able to monopolized around 90% of the oil market in North America.
The south improvement company largely increased the number of oil and railroad companies in southern states. Because of the increase in numbers, the market for oil and railroad companies became saturated. This lead many of his competitors to bankruptcy, which is why the competitors called it a conspiracy.
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It increased the demand for slave labor to grow cotton.
Many great European powers had been exploiting China's weak economic system to enforce their own trade regulations for years. The United States simply wanted to join the fray, so the Open Door notes were sent to the European powers basically stating, "Hey, you guys can't own all of China, make sure that all countries get to trade equally with them."
Just as a side note, the Open Door policy with China was extremely hypocritical for the United States, as the Monroe Doctrine of 1823 basically stated that none of the European powers could interfere with the Western Hemisphere... While no one was allowed to touch the Americas, the United States was apparently allowed to mess with the rest of the world.
Rheumatic fever he also delt with anxiety, depression, and he had a bipolar disorder
