Answer:
A
Explanation:
The mountains will increase their elevation over time
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Answer:
Explanation:
Pharmacophore (pharmacology) - The molecular framework responsible for a drug's biological activity. According to IUPAC — A pharmacophore is the ensemble of steric and electronic features that is necessary to ensure the optimal supramolecular interactions with a specific biological target structure and to trigger (or to block) its biological response.
Privileged structures are defined as molecular frameworks which are able of providing useful ligands for more than one type of receptor or enzyme target by judicious structural modifications.
1) The 1,4-dihydropyridine ring is present in many biologically important molecules that acts as an important scaffold for cardiovascular drug - a calcium antagonists and although it is technically not considered as a pharmacophore, it is considered as a privileged structure.
1,4-Dihydropyridine (DHP), belongs to the class of calcium antagonist that inhibits the influx of extracellular Ca+2 through the L-type voltage-dependent calcium channels.
A positional substitution in the 4-position is feasible in the heterocyclic ring which in turn culminates in various calcium channel antagonist activities and this heterocyclic ring is the common feature for various pharmacological activities such as anti-inflammatory activity, analgesic activity,
antihypertensive, antianginal, antitumor, antitubercular activity and antithrombotic .
Position on the heterocyclic ring binds to the L-type channel and also to N-type channel on membranes.
2.) The bioisosteres are not a suitable bioisostere for the traditional C-4 aryl or heteroaryl substitution which is necessary for calcium ion blockage thereby inhibiting it to function with the mechanism shared above.
Answer:
the difference between frog and grasshopper is that
frog is a small tailless amphibian of the order anura that typically hops or frog can be (offensive) a french person or frog can be a leather or fabric loop used to attach a sword or bayonet, or its scabbard, to a waist or shoulder belt
while grasshopper is a herbivorous insect of the order orthoptera noted for its ability to jump long distances.
frog is to hunt or trap frogs or frog can be to ornament or fasten a coat, etc with frogs or frog can be to unravel (a knitted garment).
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<span>The culture contains 2*10^8 bacteria before it was exposed to ionizing radiation which kills 99.99% of the bacteria. The number of bacteria left after the radiation would be:
final number= initial number * (100%- radiation kill rate)
</span>final number= 2*10^8<span> *(100%-99.99%)
</span>final number= 2*10^8 *(0.01%)
final number= 2*10^8 * 10^-6
final number= 2*10^(8-6)
final number= 2*10^2
Yes you do because you’re energy will get worn out so you will get tired
