The skin is the body's largest organ. 30% of the cardiac output goes to direct the flow of blood to the skin for cooling; the evaporation of perspiration will act to reduce body temperature. So, the skin receives approximately 30% of all the blood circulating through the body.When the body is at rest, this percent is 20%.
They tried to connect the idea of stars with the sun
They are symmetrically arranged.
The value of n, the Hill coefficient, for hemoglobin is about 2 to 3 times as great as the value for myoglobin.
Hill Equation
The two closely related equations that help to explain the binding of macromolecules to ligands are called the Hill equation. It helps to quantify the interaction between various ligand binding sites.
Hill coefficient
It is used to describe the cooperativity of ligand binding. It can be positive and negative depending on the value of the Hill coefficient. If the value of the Hill coefficient is more than one then it exhibits positively cooperative binding and if it is less than one then it exhibits negatively cooperative binding. Then there is the noncooperative binding where the Hill coefficient value is one. As for the hemoglobin and myoglobin, the values are,
- Hill coefficient of hemoglobin is 2.7 - 3.
- Hill coefficient of myoglobin is 1.0.
Thus hemoglobin is positively cooperative and myoglobin exhibits noncooperative binding.
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