Question

What are the advantages to using prokaryotic as host systems for genetic engineering? What are the limitations to genetic engineering in prokaryotes? Are these limitations addressable in single cell eukaryotic systems? Give an example of bioproduction in each system.

Answer 1

Answer and Explanation:

The manipulation of the gene is called genetic engineering. In genetic engineering, fragments of genes are cloned by leading the genes into the host cell. The advantage of using a prokaryotic host system in genetic engineering is that bacterial cells are used to produce commercially significant products. For example, human growth hormone helps to treat dwarfism, and human insulin production, which is used to treat diabetes. The bacterium P.putida is created by genetic engineering, which is used to break down petroleum products. Genetic engineering also carries some potential risks, such as transferring the selected gene into another speice, benefit one species can harm another speice. Therefore genetic engineering must be used in limit in prokaryotes. These limitations are also addressable in single-cell eukaryotic systems. Biologics-based therapeutic medicines such as a vaccine, gene therapies, and cell therapies known as bioproduction are produced. Medicines are so complex that they can only be formed in a living system. Biopharmaceuticals, value-added food, fuels, chemicals, antibiotics, and many other products are produced by bioproduction.