Portugal with arrival of Columbus in 1492
They fished whales and fish. They traded with the Indians, built ships, farmed grain, rice, and wheat and manufactured iron goods.
Isolation and quarantine are public health practices used to protect the public by preventing exposure to people who have or may have a contagious disease.
Isolation separates sick people with a contagious disease from people who are not sick.
Quarantine separates and restricts the movement of people who were exposed to a contagious disease to see if they become sick. These people may have been exposed to a disease and do not know it, or they may have the disease but do not show symptoms.
Expand its power and control over Eastern Europe