A nuclear war between the U.S. and the U.S.U almost became a reality because the Soviet Union stuck missiles in Cuba... I think thats right :)
Anti-Federalists were against the Constitution, so I'm fairly certain that the rest of that statement goes:
According to the Anti-Federalists, a governing document such as the Constitution should most certainly fail to protect the rights of individuals and the states.
That's the most I've got with how much you gave, I'll probably need specific choices to choose from for a more satisfying and accurate answer.
I read a book series on this subject and I'm pretty sure its D. All of the above. Because many African Americans were indeed looking for job opportunities instead of being slaves and working on plantations, would face rarely any harsh racism there, and well the government didn't exactly help but there was many operations aiding the move.