Answer: Kidney
Explanation:
Kidney is a structure that is located toward the dorsal side of the body, lateral and superior to the hamstring but inferior to the heart.
The kidneys are a pair of bean shaped organs that are located at the downward part of the rib cage. The body of humans consists of two kidneys one kidney on each side of the spine and they're responsible for the filtering of excess water, waste products, and other impurities out of the human body.
Answer and Explanation:
The Huntington disease is caused by a mutation in the gene that codifies for the Huntingtin protein (Htt). The mutation produces an altered form of the protein leading to the neuron´s death in certain areas of the brain.
The Huntington disease characterizes for being,
- Hereditary, passing from generation to generation. To express the disease, a person must have been born with an altered gene.
- Autosomal, affecting men and women equally, because the mutated gene is located on an autosomal chromosome.
- Dominant, which means that by getting only one copy of the altered gene coming from any of the parents, the receiving person will express the disease. The mutation in the gene dominates over the normal gene copy.
- Expressed by heterozygosis. Most people affected by the disease are heterozygous, with a normal copy and a mutated copy.
There are just a few cases all around the world (3% approximately) in which the disease is expressed with no family history. The progenitors are not affected by the mutation. These cases are very rare and are called <u>"de-novo" mutations.</u> A new mutation is spontaneously produced and it is not inherited from any of the parentals. It consists of an increase in the number of CAG repetitions. In a normal person, the number of CAG repetitions is less than 35. When there are 40 or more repetitions it occurs the disease. But when there are between 35 and 39 repetitions, the penetrance of the disease is incomplete. This is a "gray zone". Those alleles that fall in the gray zone are unstable and might produce the HD. Individuals with these unstable alleles have a tendency to increase the number of repetitions from generation to generation until the number reaches 40 repetitions and the person expresses the disease. This <u>usually occurs in the paternal germinal line</u>, as it is particularly unstable in sperm and probably meiosis greatly affects their instability, causing an increase in the number of CAG repeats.
Answer:
Vacuoles are storage sacs used for storing liquid and solid contents.they are small in animal cells and large in plant cells.in plant cells vacuoles are full of cell sap and provide turgidity and rigidity to the cell.in single celled organisms like amoeba,the food vacuole contain the food item that amoeba has consumed.in some unicellular organisms specialised vacuoles also play important role in expelling excess water and some waste from the cell.
Explanation:
