I believe its D. depletion, environmental, job<span />
Answer:
Hey sorry if I can't answer you question but why did you friend me ?
Explanation:
A man who stands by one's side, does the handiwork for the person and relieves them of difficulties or overwhelming work.
changes to the mutation is harmful
mutations are basic input of a organism
so playing with mutations is like inviting danger
it will give beneficial and neutral defects to the organism and may take life of it.
the biggest example is playing with virus which caused corona