The diary of Louis and Clark, or Louis and Clark's adventures through out the Louisiana purchase land, with Sacagawea
A - to pay off the debts from the French and Indian War
The British Parliment felt they had the right to tax the colonies to pay off their war debts they had incurred during the Seven Years' War.
This combination or a mix of people could lead to confrontations or even wars due to their differences which might be based on hatred, intolerance and opposite beliefs. On the other hand, culture might be threatened, they would result lost because of the combination.
Difficulties to communicate because of the different languages people use.