So, Renaissance is similar to saying the word reawakening, revival or rebirth & people used to call certain periods of time are known as the "Renaissance period", in this period people (mainly from Europe) used to have a keen interest in the history or the past of their countries culture- arts, literature & even social & political change.
the answer is d. try to kill herself. the doctor is suspicious of something, but 'the means of all annoyance' most likely means anything she can harm herself with.