A lack of trade with other nations outside East Asia has been a serious cost of industrialization in East Asia.
Colonists who lived in the region where the proclamation line did not touch, were angered because they were forced to move towards the cities and ocean. They felt that choosing a home was more important than being under a monarchy that would move them away.
The Treaty of Ghent was signed by British and American representatives at Ghent, Belgium, ending the War of 1812. By terms of the treaty, all conquered territory was to be returned, and commissions were planned to settle the boundary of the United States and Canada.