This could be answered, theoretically, in many different ways. All of which might sound a bit dirty. The translation of the sentence is: "What ___ ___ (to) do to Juan on vacation?" I could fill in the blanks with "tú quieres" which would translate the sentence to "What do you want to do to Juan on vacation?" Without choices, that is the best I got.
The answer for number 1 and 2
1-Hoy yo voy
2-soy
1 Qué.
2 Quien.
3 a qué hora.
4 cuánto.
5 quienes.
6 cuando.
