A deficiency of dopamine is responsible for the signs and symptoms of Parkinson's disease.
Parkinson's disease is characterized by gradual degeneration of neurons in a section of the brain. In normal conditions, these neurons release a chemical substance known as dopamine which is important for the brain.
Dopamine is a neurotransmitter which facilitates communication amongst different parts of the brain that is responsible for smooth muscle activity and proper nerve operation.
Parkinson’s disease is a disorder generally associated with uncontrollable movements like tremors, rigidity as well as problems linked with maintaining body balance and coordination. Symptoms generally develop slowly and intensify over the period.
People may experience trouble in walking and talking with the advancement of the disease. The patients may also exhibit mental as well as behavioral alterations, sleep trouble, depression, memory problems and lethargy.
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1. a) predation is when one organism is harmed and the other is benefited. An example of this is when a predator eats/hunts its prey - like a lion eating a lamb
b) commensalism is when one organism benefits from the other and the second organism is not affected. An example of this are the barnicles on a whale
c) symbiosis is the long-term interaction between two different biological organisms
d) parasitism is when one organism is harmed while the other is benefited
Answer: 3 stages- glycolysis, pyruvate oxidation, the citric acid or Krebs cycle, and oxidative phosphorylation. In glycolysis, the beginning process of all types of cellular respiration, two molecules of ATP are used to attach 2 phosphate groups to a glucose molecule, which is broken down into 2 separate 3-carbon PGAL molecules. PGAL releases electrons and hydrogen ions to the electron carrier molecule NADP+. A carboxyl group is removed from pyruvate and released as carbon dioxide. The two-carbon molecule from the first step is oxidized, and NAD+ accepts the electrons to form NADH. The oxidized two-carbon molecule, an acetyl group, is attached to Coenzyme A to form acetyl CoA. The citric acid cycle, where acetyl CoA is modified in the mitochondria to produce energy precursors in preparation for the next step. Oxidative phosphorylation, the process where electron transport from the energy precursors from the citric acid cycle (step 3) leads to the phosphorylation of ADP, producing ATP. The space between the inner and outer membrane is called the intermembrane space. The space enclosed by the inner membrane is called the matrix. The second stage of cellular respiration, the Krebs cycle, takes place in the matrix. The third stage, electron transport, takes place on the inner membrane.
Explanation:
The pluripotent, undifferentiated cells in the bone marrow that give rise to the formed elements are called stem cells.
Pluripotent stem cells have the ability to undergo self-renewal and to give rise to all cells of the tissues of the body. However, this definition has been recently complicated by the existence of distinct cellular states that display these features.
There are two types of pluripotent stem cells :
- Embryonic stem cells (ESCs)
- Induced pluripotent stem cells
Embryonic stem cells are derived from the inner cell mass (ICM) of pre-implantation embryos and can be indefinitely maintained and expanded in the pluripotent state in vitro. Pluripotent stem cells can also be obtained by inducing dedifferentiation of adult somatic cells through a recently developed in vitro technology, known as cell reprogramming.
Similarly to Embryonic stem cells , Induced pluripotent stem cells can be expanded indefinitely and they are capable to differentiate in all the derivatives of the three germ layers.
Another intriguing features of being pluripotent is its reliance on gene expression heterogeneity.
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