Answer:
Alzheimer's disease
Explanation:
Neurodegenerative disease is the condition which is caused when the fundamental unit of the nervous system called neurons degenerate. The two main neurodegenerative diseases are Alzheimer's disease and Parkinson's disease.
The Parkinson's disease is the disease which affects the musculoskeletal system but the Alzheimer's patient is not able to recall the memory and events, therefore, interfere with the deterioration of the cognitive and emotional abilities.
Thus, Alzheimer's is the correct answer.
Answer:
Methotrexate inhibits the synthesis of DNA, RNA, and protein synthesis of the cells in the experiment.
Explanation:
Methotrexate competitively inhibits the enzyme dihydrofolate reductase (DHFR) which is involved in the synthesis of tetrahydrofolate from the inactive dihydrofolate. The methotrexate blocks the enzyme by binding to its active site thereby preventing further reaction of the dihydrofolate reductase enzyme and dihydrofolate. Tetrahydrofolate is a useful material for the de novo synthesis of thymidine, a nucleoside. And without thymidine, DNA synthesis is hindered. Methotrexate therefore inhibits the synthesis of DNA, RNA, thymidylates and of course protein synthesis.
