The gene expression of the organism may be affected by the environment. This includes the outside ecosphere where the entire creature and organism are situated or progresses, and also as the organism's interior ecosphere, these consist of the aspects of metabolism and hormones. Even though the structure of genes is unaffected by the environment, the gene expression (how the genes work) will be affected. Factors in the environment like drugs, foods, and toxins may result in some epigenetic changes by changing how the DNA bind by the molecules and the structure change of the proteins that the DNA wraps.
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Irredentism is related to, but distinct from, secession. Irredentism is the process by which a part of an existing state breaks away and merges with another, whereas in secession merging does not take place. The importance of irredentism in international relations is based on the intersection between nationalism and the causes of war; because such a movement invariably means taking land from another state, irredentist claims have been known to provoke ethnic conflicts and territorial aggression. The continued discord between countries and states means that the potential for irredentist wars remains serious. The Admission to the Union Clause of the United States Constitution (often called the New States Clause) found at Article IV, Section 3, Clause 1, authorizes the U.S. Congress to admit new states into the Union (beyond the thirteen already in existence at the time the Constitution went into effect). The Constitution went into effect on June 21, 1788, after ratification by 9 of the 13 states, and the federal government began operations under it on March 4, 1789.[1] Since then, 37 states have been admitted into the Union. Each new state has been admitted on an equal footing with those already in existence.[2]
Of the 37 states admitted to the Union by Congress, all but six have been established within an existing U.S. organized incorporated territory. A state so created might encompass all or a portion of a territory. When the people of a territory or a region thereof have grown to a sufficient population and make their desire for statehood known to the federal government, in most cases Congress passed an enabling act authorizing the people of that territory or region to frame a proposed state constitution as a step toward admission to the Union. Although the use of an enabling act was a common historic practice, several states were admitted to the Union without one.
In many instances, an enabling act would detail the mechanism by which the territory would be admitted as a state following ratification of their constitution and election of state officers. Although the use of such an act is a traditional historic practice, several territories have drafted constitutions for submission to Congress absent an enabling act and were subsequently admitted. The broad outline for this process was established by the Land Ordinance of 1784 and the 1787 Northwest Ordinance, both of which predate the U.S. Constitution.
I think its B but possibly C