The Great Depression, it wasn't that great though.
The people living in the colony of Jamestown had a very big problem with the swampy surroundings because the swamp was attracting lots of mosquitoes, and the mosquitoes were transporting diseases with them. Because there were lots of mosquitoes, people were getting stung by them on a daily basis and it happened very often that they would get some disease from them, and while some diseases did not caused big problems, some were fatal.
Answer: While it was true that the cotton gin reduced the labor of removing seeds, it did not reduce the need for enslaved labor to grow and pick the cotton. In fact, the opposite occurred. Cotton growing became so profitable for enslavers that it greatly increased their demand for both land and enslaved labor.
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