Answer:
Lichens are not parasitic when they grow on trees, they just use the tree bark as a home. They enrich the soil by trapping water, dust and silt. When lichens die they contribute organic matter to the soil, improving the soil so that other plants can grow there.
Uterus<span>Once girls become sexually mature, the outer labia and the mons pubis are covered by pubic hair. A female's internal reproductive organs are the vagina, uterus,fallopian tubes, and ovaries. The vagina is a muscular, hollow tube that extends from the vaginal opening to the <span>uterus</span></span>
Yes, it is true that Methylation of EZH2 by PRMT1 regulates its stability and promotes breast cancer metastasis.
Enhancer of zeste homolog 2 (EZH2), a key histone methyltransferase and EMT inducer, is overexpressed in diverse carcinomas, including breast cancer.
However, the molecular mechanisms of EZH2 dysregulation in cancers are still largely unknown. Here, we discover that EZH2 is asymmetrically dimethylated at R342 (meR342-EZH2) by PRMT1.
meR342-EZH2 was found to inhibit the CDK1-mediated phosphorylation of EZH2 at T345 and T487, thereby attenuating EZH2 ubiquitylation mediated by the E3 ligase TRAF6.
We also demonstrate that meR342-EZH2 resulted in a decrease in EZH2 target gene expression, but an increase in breast cancer cell EMT, invasion and metastasis.
Moreover, we confirm the positive correlations among PRMT1, meR342-EZH2 and EZH2 expression in the breast cancer tissues. Finally, we report that high expression levels of meR342-EZH2 predict a poor clinical outcome in breast cancer patients.
Our findings may provide a novel diagnostic target and promising therapeutic target for breast cancer metastasis.
Learn more about breast cancer here : brainly.com/question/6747562
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The answer is (A) stabilizing selection. Stabilizing selection favors the average in a population. In this case, babies that are born at a normal body weight, or an average between the two extremes of underweight and large, tend to have more favorable outcomes.
Answer:
from 60 to 100 beats per minute
