B, metals, nonmentals all bond to be stable
        
                    
             
        
        
        
Answer:
Reasons why Maria will have tissue ischemia: 
1. Because of evident problems with her blood circulation, this means insuficent blood flow. This shows in the edema she has.
2. The ischemia can lead to hypoxia because of the lack of oxygen in the blood stream to reach to the tissue cells. 
Explanation:
Ischemia is a health problem characterized by the lack of oxygen that the bloods transports to the tissues in the body. 
Hypoxia is related to the unsuficient oxigen supply gettin to a certain regions of the body or to the entire body.
 
        
                    
             
        
        
        
In terms of macromolecules, needed and utilized by organisms to carry out essential metabolic chemical reactions and for maintaining structure would be Lipids. 
Lipid based molecules or Fats tend to store the most energy, as breaking chemical bonds connecting fatty acid chains of long hydrocarbons releases quite a bit of energy.
        
             
        
        
        
By the ligand receptors on the surface of the cell membrane. How do transport proteins make it easier for certain molecules to diffuse across a membrane.  
the binding of a signaling molecule, or ligand, to its receiving molecule, or receptor.