If the plague, also referred to as ''black death'', didn't occurred in Europe, the continent would have had a much larger population for starters. Because of the plague and the huge loss of population, Europe faced huge problems from social, economic, and military perspective, but if it hadn't occurred, Europe would have been much stronger and the progress of the continent would have been evident and bigger earlier in time. Considering the European colonialism, it was also going to have a huge global effect because there was going to be a much larger number of people migrating into the European colonies later on.
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Answer:
Expansionism was the most important issue prevailing during the era of the Manifest Destiny. There was a decisive question of expansion of slavery. Whether there'll be slavery in the new areas that were settled.
The northerners and the southerners defined the Manifest Destiny in different ways. The Manifest Destiny is concerned with the increase of capitalism and democracy around the nation. Hence Expansion of slavery was the issue during Manifest Destiny era.
:His head stone reads "I know no north,no south, no east, no west"