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bija089 [108]
3 years ago
12

CTLs can kill cells infected with viruses or intracellular bacteria. They also can kill cancerous cells. How might an infected o

r cancerous cell evade immune control by CTLs?
a. Increased expression of MHC class II molecules.
b. Increased expression of MHC class I molecules.
c. Decreased expression of MHC class I molecules.
Biology
1 answer:
MatroZZZ [7]3 years ago
8 0

Answer: The correct option is C (Decreased expression of MHC class I molecules.)

Explanation:

The lymphocyte is the major type of white blood cells which is divided into two:

--> B Lymphocyte and

--> T Lymphocyte

The T Lymphocyte is further divided into two namely:

--> T helper cells and

--> Cytotoxic T Lymphocyte (CTL)

The T lymphocyte cells recognize a non self target such as a pathogen only after pathogen has been processed and it's antigen presented in combination with a complex known as the Major histocompatibility Complex ( MHC). There are two types of MHC which includes Type 1 and Type 2 MHC.

The cytotoxic T Lymphocyte only recognize antigen combined with Class 1 MHC.

Some virus mechanism of action, while invading some target cells, is to reduce the normal levels of surface class 1 MHC in order to evade or escape the immune control by cytotoxic T Lymphocyte. Therefore the correct statement is decreased expression of MHC class I molecules.

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