Question

You have engineered a protein that contains a nuclear localization signal, a nuclear export signal, a C-terminal peroxisomal targeting signal, and an import signal for the endoplasmic reticulum. with all of these signal sequences, where would you expect to find the protein after its synthesis?

Answer 1

Answer:

The correct answer is - Endoplasmic reticulum

Explanation:

In this case, the N-terminal endoplasmic reticulum signal sequence of the engineered protein is recognized primarily. This signal is used to target the particular protein co-translationally, to the endoplasmic reticulum for post-translational modifications or changes.

Such post-modifications are glycosylation that taken place in the lumen of the endoplasmic reticulum. Other than Glycosylation Protein phosphorylation , Sumoylation and Ubiquitination, are other changes or modifications.