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Answer:
Sickle cell anemia refers to a recessive inheritance disorder, in which every individual carries two copies of a gene. In normal individuals, both the copies of the globin gene are normal, and they generate 2 and 4 kb fragments of DNA on digestion by BseR1. A patient with sickle cell anemia is homozygous for the recessive gene and exhibits a mutation in both the copies of a globin gene.
Therefore, BseR1 could not digest the globin gene and generate a single 6Kb fragment of DNA. In a patient acting as a carrier, one copy of a globin gene is mutated and the other is normal. As a consequence, BseR1 digestion generates 6kb of the fragment of DNA (mutated copy) and 4 and 2 kb from the normal copy of a gene.
Answer:
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Explanation:
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There are TWO different ways by which homologous pairs of two chromosomes line up along the equatorial plate. In meiosis, these differences will be evidenced by the genetic makeup of daughter cells.
During metaphase, homo-logous chromosomes are lined up at the middle of the cell (i.e., the equator plate).
Subsequently, during anaphase, homo-logous chromosomes are separated, thereby daughter cells will receive only one homo-logous chromosome of the chromosome pair.
Meiosis is a type of cell division characterized by the independent assortment of chromosomes, which is due to the random assortment of homo-logous chromosomes at the metaphase plate.
This independent assortment offers unique compositions of alleles in daughter (meiotic) cells.
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