Answer:
The correct option is: <em>a deficiency of dopamine in the substantia nigra.</em>
Explanation:
The substantia nigra is the principal site involved in the physiopathology of Parkinson´s disease.
Cells from this area degenerate and die progressively causing important degeneration in the central nervous system. The cells that die -with no known reason- are those that produce dopamine and proportionate dopaminergic innervation to the encephalon. In fact, almost all the symptoms exhibited by patients with the disease can be explained by the lack of dopamine in the substantia nigra.
This area uses the neurotransmitter to communicate neurons from the base ganglia. Ganglia are responsible of modulating and modifying movements.
The nigrostriatal system participates in planning and automatic execution of learned movements. When the ganglia activity decreases, so it does the amount and velocity of movements, something typical of the disease.
<span>It is usually the best practice to start checking from his or her lower limbs, toes and gradually progress upwards ,legs waist , stomach, chest, hands and the head lastly. In short, do it from the bottom to the top.</span>
Well a person breathes harder when he/she exercizing because you are working hard and your body is not used to it so your trying to pass more air through the lungs
One of the many changes are the seasons, ex Winter, Spring, Summer, Fall
