The ancient civilization of the Incas, which was in South America, was taken over by the Spanish conquistador Francisco Pizarro in 1535. The Incan king at the time, Atahualpa (I think I spelled that right), was held prisoner and eventually killed by the Spanish.
Hope this helps! Please let me know if I'm wrong :)
The Civil War started because of uncompromising differences between the free and slave states over the power of the national government to prohibit slavery in the territories that had not yet become. I believe so.