Probes that bind under very stringent hybridization conditions resulting in the differential binding over one nucleotide are cal

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Probes that bind under very stringent hybridization conditions resulting in the differential binding over one nucleotide are cal

led ________. Probes that bind under very stringent hybridization conditions resulting in the differential binding over one nucleotide are called ________. short, variable repeats VNTRs microsatellites allele-specific oligonucleotides (ASOs) generation-specific probes

Biology

1 answer:

Vadim26 [7] · Answer 1 · 2022-11-19T22:46:48+03:00

Answer:

allele-specific oligonucleotides (ASOs)

Explanation:

An allele-specific oligonucleotide (ASO) is a piece of synthetic DNA that is short and usually a complementary to the sequence of a target DNA, It is an oligonucleotide of 15–21 nucleotide bases in length.

It acts as a probe in southern blot assay or simpler Dot blot assay to identify the presence of a target.

It is an important research tool in genetic testing, forensics, and Molecular Biology.

The probes can detect a difference of as little as 1 base in the sequence targeted.