The question that leaves Brutus sleep-deprived at the beginning of Act 2 is when he asks Lucius what day it was. It made him awake thinking about his plan to kill Caesar. He thinks that the leader as become corrupt and unreliable.
A simile can be found when using "like" or "as" between two things. Example: I'm as happy as a clown.
Your question would be a metaphor. Both things are being compared to a science expieriment, probably meaning that they need to have an outcome, but it isn't known for sure if it will be a good or bad outcome.
Things like this can be taken many ways, so if you think something else, I'm sure it would work as well.
it is troublesome because there's some people who just cant handle the black uprising war
This is called using context clues.