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What effect did the Columbian exchange have on the Native American population?

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Some of the largest indigenous groups are the Wayuu, the Arhuacos, the Muisca, the Kuna people, the Witoto, the Páez, the Tucano and the Guahibo. The departaments (departamentos) with the biggest indigenous population are Cauca, La Guajira and Nariño.

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