The answer should be D. Electrons
Answer:
genetic diversity
red yellow and orange bell peppers
individuals of the same lizard species
species diversity
a park has eighty species of trees
five bird species are at a bird feeder
Explanation:
Klinefelter's syndrome is a result of chromosomal nondisjunction mutations.
<h3>What is Klinefelter's syndrome?</h3>
Klinefelter's syndrome is a result of the presence of an extra X chromosome in germinal cells.
In genetics, this type of mutation is referred to as chromosomal nondisjunction (aneuploidies).
In conclusion, Klinefelter's syndrome is due to chromosomal nondisjunction.
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Yes, it is true that Methylation of EZH2 by PRMT1 regulates its stability and promotes breast cancer metastasis.
Enhancer of zeste homolog 2 (EZH2), a key histone methyltransferase and EMT inducer, is overexpressed in diverse carcinomas, including breast cancer.
However, the molecular mechanisms of EZH2 dysregulation in cancers are still largely unknown. Here, we discover that EZH2 is asymmetrically dimethylated at R342 (meR342-EZH2) by PRMT1.
meR342-EZH2 was found to inhibit the CDK1-mediated phosphorylation of EZH2 at T345 and T487, thereby attenuating EZH2 ubiquitylation mediated by the E3 ligase TRAF6.
We also demonstrate that meR342-EZH2 resulted in a decrease in EZH2 target gene expression, but an increase in breast cancer cell EMT, invasion and metastasis.
Moreover, we confirm the positive correlations among PRMT1, meR342-EZH2 and EZH2 expression in the breast cancer tissues. Finally, we report that high expression levels of meR342-EZH2 predict a poor clinical outcome in breast cancer patients.
Our findings may provide a novel diagnostic target and promising therapeutic target for breast cancer metastasis.
Learn more about breast cancer here : brainly.com/question/6747562
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Answer:
for food, water, shelter, mates, light, and other resources needed for survival and reproduction.
Explanation:
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