He was acting on the manifest destiny.
The correct answer is Malaria
Malaria was a huge problem since it couldn't be treated and people mostly died from it. It prevented numerous explorers from venturing into places like Africa where Malaria was running rampant due to the huge amount of mosquitoes. When it was discovered, it enabled numerous people to live at ease because they could not live with the disease or prevent getting it.
The Indian removal act was to allow President Andrew Jackson to negotiate with southern tribes for their removal to western lands. There was nothing in the west to help them prosper so a lot of the Native Americans died along the way (trail of tears). Im an enrolled member of the Crow Tribe so I'm pretty educated in these departments. Hope this helps!
Answer:
a forcible overthrow of a government or social order, in favor of a new system.
Explanation:
The country does not have enough natural resources to support its economy.