Mostly because our modern civilizations were born there. "The region saw the development of some of the earliest human civilizations,
which flourished thanks to the water supplies and agricultural
resources available in the Fertile Crescent. Technological advances made
in the region include the development of writing, glass, the wheel, agriculture, and the use of irrigation." ~Wikipedia
wealth of the Italian city-state played an important role in the Renaissance. This wealth allowed prominent families to support artists, scientists, and philosophers spurring on new ideas and artistic movements