Before buying the 2nd largest house, he lived in Stratford-upon-Avon
It depends.
'Mike and Mary's Pizza' is most likely a place, and a noun is a person, place, or thing. If it is a person's name, a place (such as a street name, name of a place, a city, a country, a town..) it must be capitalized. Just regular English rules.
Now, if the Mike and Mary HAD a pizza, you would not need to capitalize pizza considering it is the object. Here's an example of a sentence where you wouldn't need to capitalize pizza - "Mike and Mary's pizza was cheese." Now here's an example of where you would want to capitalize pizza - "I am headed to Mike and Mary's Pizza to get some food."
One of the benefits of asexual reproduction is that only individual parents are demanded. When the living thing is prepared to generate offspring, it could do so accordingly without procrastinating for a sufficient comrade.
