Person who opposes another in a contest, battle, etc
2. (Anatomy) anatomy an opponent muscle
adj
3. opposite, as in position
4. (Anatomy) anatomy (of a muscle) bringing two parts into opposition
5. opposing; contrary
[C16: from Latin oppōnere to oppose, from ob- against + pōnere to place]
There can be numerous challenges but the biggest are sickness, lack of proper food and drink, increase in pollution in the area, and increased death due to these factors, Hope this helped! ^-^
I think it would be China because it's the most developed country in Asia and is a very big impact on international trade.
The sugar act of 1764 was the most hated of tax acts I think
