<u>The road to Santa Fe was a transport route opened by the Spaniards at the end of the 18th century and later used by the Americans in the 19th century</u>, <em><u>crossing the southwest of North America connecting the city of Independence, Missouri, with Santa Fe, New Mexico</u></em>. <u>The route was used to transport manufactured products</u>.
<em><u>The answer is</u></em>: <u>Let it be a transport route for manufactured products.</u>
