Induced depression of single neurons in brain areas with opiate receptors
- Enkephalin, applied microiontophoretically, depressed spontaneous and glutamate-induced firing of one neuron in frontal cortex, caudate nucleus, and periaqueductal gray matter, where enkephalin and high concentrations of opiate receptors are met.
- More than one depressions were blocked by the specific narcotic antagonist naloxone. The results are durable with a neurotransmitter or neuromodulator role for this new brain pentapeptide.
- Opium derivatives have been in medical use for the last 2000 years, and may be longer than any other class of drugs
- . The brain regions which was involved in these actions have been identified in some instances by local microinjection of pmole quantities of opioids.
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"27 days, 7 hours, and 43 minutes for our Moon to complete one full orbit around Earth"
Humans are warm blooded and can't be cold blooded because of the environment we live in. We can't sit still during the winter and soak up warmth from the sun.
