Answer:
Phase III
Explanation:
The given condition fall in the trial phase (Phase III) of cinical study which aims to:
- Determine drug's effectiveness (primary goal)
- Determine long-term drug safety
- Confirm findings
In Phase III, randomised, double-blind, placebo-controlled, parallel group study is majorly to evaluate the efficacy and safety of placebo in episodic migraine prevention in children (6 to < 12 years of age) and adolescents (12 to < 18 years of age).
The trial consists of four phases: screening; double-blind therapy period for 24 weeks in which placebo or Erenumab is given to subject as dose 1, dose 2 or dose 3 (based on the participant's body weight) once a month via subcutaneous injection; optional dose level blinded extension phase (40 weeks) which involves subjects recieve dose1, 2 and 3 of placebo, and at last it follows a safety follow-up phase for 12 weeks (after 16 weeks of the last dose of investigational drug).
Hence, the clinical phase is phase III.
Answer:
The Ray- Finned Fish has a bony skeleton just like crocodiles. Crocodiles evolved more and adapted to their environment. Along the way Crocodiles grew to have four limbs, were born from an amniotic egg, and then their eggs also have shells, unlike the Ray-finned fish. Therefore the three characteristics they do NOT have in common are: Four Limbs, Amniotic Egg, and Eggs with Shells. The one trait they do have in common is Bony Skeletons. They also both have vertebrae.
Answer:
In human vision, the cone visual opsins are grouped into four photoreceptor protein families LWS, SWS1, SWS2, RH2
.
- SWS1: produce pigments sensitive to very short wavelengths, UV-violet, 360-450 nm.
- SWS2: produce pigments sensitive to short wavelengths, blue, 450-495 nm
- RH2: produce pigments sensitive to medium wavelengths, green, 495-560 nm
- LWS: produce pigments sensitive to long wavelengths, yellow-red, 560-770nm.
Explanation:
Photoreceptor proteins are light-sensitive proteins that mediate light-induced signal transduction, thus they are involved in the sensing and response to light in a variety of organisms.
The photoreceptor proteins are classified based on the chemical structure of the chromophores involved, the light absorption and on the protein sequence.
This photoreceptor proteins are located at the cone photoreceptor cells and are responsible of photopic vision.
For scotopic vision, rhodopsin is responsible. Rhodopsins are the visual pigments (visual purple) of the rod photoreceptor cell in the retina. They are responsible of human vision in dim light, as it contains a sensory protein that converts light into an electric signal.
Answer:
O coral bleaching
Explanation:
Without the algae, corals lose their color and turn white. This is called “coral bleaching “.
Answer:
The correct answer is - Rotating Cloud.
Explanation:
According to the nebular hypothesis presented by the Swedish philosopher Emanuel Swedenborg in 1734 that says that the Sun and all the other planets of our Solar System evolved from a giant cloud of molecular gas and dust. This huge cloud could have been the result of a shock waves from a supernova or any passing star, but the end result was a gravitational collapse at the center of the cloud.
Thus, the correct answer is - our solar system evolved from a huge Rotating cloud.
