<span>Minimal residual cancer cells may not be detected in surgical margins of oral squamous cell carcinoma (OSCC) with routine histological examination. Using molecular markers at surgical margins can be helpful. We attempted to evaluate the MMP-9 and E-cadherin expression in OSCC samples and tumor-free surgical margins and association with clinicopathological factors. We examined E-cadherin and MMP-9 expression in 58 OSCCs including 19 grade I, 21 grade II and 18 grade III with histological tumor-free surgical margins by immunohistochemistry. Specimens were also divided in two groups: 19 samples as an early and 39 as an advanced stage. For E-cadherin in OSCCs and surgical margins, significant difference was observed between poor and moderate tumor differentiation. Different stages of OSCC demonstrated significant differences with higher expression in early stage tumors. For surgical margins, 82.1% of advanced and 84.2% of early stage samples demonstrated immunoreactivity. Both OSCC samples and surgical margins demonstrated significant differences for MMP-9 between stages with higher immunoreactivity in advanced stage, whereas there were not differences between different grades in surgical margins. E-cadherin and MMP-9 expression at histologically negative surgical margins shows the significance of these markers for prognostic values in OSCC patients with E-cadherin being the preferred predictor.</span>
Answer:
Step-by-step explanation:
5 x 9 = 45
9 x 5 = 45
45 ÷ 9 = 5
45 ÷ 5 = 9
Answer:
Step-by-step explanation:
Where the image at
Well since there are 60 minutes in an hour with means there has 120 minutes
Divide 60 by 5 = 12 x 3 = 36
120 + 36 = 156 minutes.
Answer:
Yes, the distance from the origin to the point (8,√17) is 9 units.
Step-by-step explanation:
The equation of a circle centered at the origin with radius , r has equation:
Since the circle passes through (0,-9), the radius is 9 units because (0,-9) is 9 units from the origin.
We substitute the radius to get:
If (8,√17) lies on this circle, then it must satisfy this equation:
This is True.
This means the distance from (8,√17) is 9 units from the origin.
