Answer:
All options are correct, that is, they would all be correct for osteoarthritis.
This disease is characterized by being very painful at the joint level, it is degenerative, and mobility decreases over time.
Explanation:
Osteoarthritis is a pathology that is based on the fegenerative destruction of the joints, generating edema and loss of function, that is why it is pain.
The pain is very intense and very marked, that is why it is treated with immunosuppressive drugs and analgesics. (In addition to kinesiology and physiotherapy).
This disease decreases the functional unit and the joint space, generating possible ankylosis, pseudoarthrosis, elimination of lubricating fluid from joints and nodular structures. These nodular structures tend to be more common in the hands and are called by professionals as "drum fingers".
Those changes in an individuals' genotype that ensure genetic variation begin to be done in Metaphase, where chromosomes are aligned to the equatorial axis of the cell, and eventually, each chromosome is pulled to each pole of the cell during Anaphase I. After this process, follows telophase I, where we can say that each chromosome is given to each of the two daughter cells. We can say then that the creation of different versions of alleles begins with Telophase I.
The answer is B)
The Golgi apparatus is located in the cells. It is an extra combination of organelle similar to the ER. This was named following Camillo Golgi.
(Notice that his last name is Golgi)
When Rutherford performed his metal foil experiment, he was surprised that most of the alpha particles passed straight through the foil.
Hope this helps :)
