Its historical significance of this is that real people died during this time
It sets the scene of pre-revolutionary France and demonstrates dickens’ sympathy toward the people of France at this time. The quote is important because it still shows the humanity of the peasants before it is ripped away from them by the hatred and violence brought on by the revolution.
This is a question of morals and ethics, and the answer will depend on your own personal, subjective opinions.
On one hand, some people would say that we should experiment as much as we can - going to such lengths where the modification through genetic engineering will allow us to create new humans based on our wants and needs. We will be able to choose our baby's eye color, hair color, everything we might want to do will be possible, and for some people, that is a welcome future.
However, on the other hand, there is also a large number of people who are against such modifications, primarily because it is immoral and 'against God.' In their opinion, we are playing God, doing what we were not supposed to do, and therefore will have to pay the price.
It all depends on how you look at the subject - it is quite personal.
According to the war of 1987 the French and Indian war of Allah blah
Public speaking is more people while conversation is between less audience.