Answer:
Okay
Explanation:
Human topoisomerase I plays an important role in removing positive DNA supercoils that accumulate ahead of replication forks. It also is the target for camptothecin-based anticancer drugs that act by increasing levels of topoisomerase I-mediated DNA scission. Evidence suggests that cleavage events most likely to generate permanent genomic damage are those that occur ahead of DNA tracking systems. Therefore, it is important to characterize the ability of topoisomerase I to cleave positively supercoiled DNA. Results confirm that the human enzyme maintains higher levels of cleavage with positively as opposed to negatively supercoiled substrates in the absence or presence of anticancer drugs. Enhanced drug efficacy on positively supercoiled DNA is due primarily to an increase in baseline levels of cleavage. Sites of topoisomerase I-mediated DNA cleavage do not appear to be affected by supercoil geometry. However, rates of ligation are slower with positively supercoiled substrates. Finally, intercalators enhance topoisomerase I-mediated cleavage of negatively supercoiled substrates but not positively supercoiled or linear DNA. We suggest that these compounds act by altering the perceived topological state of the double helix, making underwound DNA appear to be overwound to the enzyme, and propose that these compounds be referred to as ‘topological poisons of topoisomerase I’
Answer:
d
Explanation:
because she need her treatment fast we cant wait there and ask her name for fifty times
Answer:
"I should increase my intake of fresh fruits and vegetables during remission"
Explanation:
Diverticulitis is an inflammation or infection in one or more small pouches in the digestive tract. After the nurses' teachings a statement that would indicate this would be "I should increase my intake of fresh fruits and vegetables during remission". This is because, even though doctors say that patients with diverticulitis should avoid high fiber diets, when in remission eating lots of fresh fruits and vegetables is known to prevent acute diverticulitis.
The correct option is (c) 70%.
The nurse would document 70% blood oxygen saturation as normal for the patient.
What is Venous oxygen saturation?
- The amount of oxygen in the blood that returns to the right side of the heart after perfusing the entire body is known as venous oxygen saturation (SvO2).
- An abnormal SvO2 results from insufficient systemic oxygenation when the oxygen supply is insufficient to meet the metabolic demands of the tissues.
- To assess the severity of tissue hypoperfusion situations and the mixed venous blood oxygen saturation levels, continuous central venous oximetry (ScvO2) monitoring may be performed.
- As blood returns to the heart and pulmonary system to be re-oxygenated, a central catheter is inserted into the superior vena cava (SVC), and a sensor on the catheter monitors the oxygen saturation of the blood in the SVC. 70% is the average ScvO2 value.
Learn more about the Oxygen saturation with the help of the given link:
brainly.com/question/28079396
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I understand that the question you are looking for is "The nurse is using continuous central venous oximetry (ScvO2) to monitor the blood oxygen saturation of a patient in shock. What value would the nurse document as normal for the patient?
(a)60%
(b)50%
(c)70%
(d)40%"
