The answer you are looking for is 53.
Solution/Explanation:
Writing out the expression first
2x+3y+6z
Substituting the given values of the variables
x=4
y=3
z=6
2(4)+3(3)+6(6)
2(4)=8
3(3)=9
6(6)=36
You will come up with 8+9+36.
From this, you will get 53.
So, therefore, the final answer to this problem is 53.
Hope this helped answer your question for you. Good day to you.