The answer is B. Melanoma
Melanocytes cells create a brown pigment called melanin and actually melanin protect deeper layer of the sins from the harmful effect of the sun
But for some people, prolonged exposure to the sun make melanocytes create an uncontrollable amount of pigment and create cancer
Changes in the size of population , age and race
Physical dependence is marked by a state of mental and physical abnormality when the drug is withdrawn.
Answer:when you cough blood leaves your heart.
Explanation: I saw a video and when some one coughed blood came out of the heart.