In human gene therapy, a genetically modified virus (a.k.a. a viral vector) can alter the genetic variation of a cell, but not all viral vectors do.
The process often begins with the delivery of or creation of a segment of viral double stranded DNA (containing the gene you want to introduce). Then typically an enzyme known as an integrase cuts the ends of the segment of viral DNA and also cuts open the cell's DNA. Then the viral DNA is integrated/ inserted into the cell's DNA. The connecting ends are ligated together and adjusted so that the nucleotide base pairs match up.
This in the future may affect the gene pool for instance if the viral DNA (your gene) was inserted in the middle of another gene or important regulatory sequence of the cell DNA, and this alteration may be passed on into offspring and become present in the gene pool, which could have bad effects.
The effects on the gene pool really depends on what the virus ends up doing. For example, it may fix the function of a damaged gene which is the goal, and allow for a working gene to be in the gene pool, which would be good. The problem with gene therapy is that it's difficult to predict 100% what the virus will do every time it is given to a patient.
But it's very important to consider that it will only affect the gene pool if the virus is able to enter and alter germ cells (reproductive cells). If the virus, enters somatic cells (regular body cells) this will not be passed on to future generations. So viruses can be designed to avoid germ cells and avoid this gene pool issue. Also, some viral vectors use viruses that do not integrate their DNA, the cells just express the viral DNA (create the desired protein from it) and over time the viral DNA is degraded/ lost which wouldn't pose this threat.
This is long, but I hope it helped!
Words thermal, thermocouple, thermos, thermel. Therm is all about heat, it’s a unit of heat. Therm is a Greek word meaning heat such as thermometer hypothermia and many more
A. it has uracil
We know the sequence is RNA because it contains uracil.
The answer is true can you tell me answer my question
Black B is dominant over chestnut color b and trotting gait T is dominant over pacing gait t. The answer is 100%. Since all offspring have at least one dominant black hair allele that overwhelms the brown hair allele, all offspring are expected to have black hair.
Phenotype refers to the physical color of a horse's coat or the way genes are expressed. Phenotype II FMF in Familial Mediterranean Fever is the onset of amyloidosis prior to the onset of his FMF with typical attacks or is an isolated finding in members of the FMF family.
White horses have pink skin. White fur mane tail, and hooves. and dark brown eyes. White is the dominant trait W at the white locus. White horse genotype must be heterozygous dominant We. Homozygous dominant because WW is more likely to cause early embryonic loss. Scientists conclude that horses were first domesticated 6,000 years ago in the western part of the Eurasian steppe, in what is now western Ukraine and Kazakhstan.
Learn more about Horse phenotype here:-brainly.com/question/26406162
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